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The security of sildenafil hasn't been analyzed in the subsequent sub-groups of individuals and its use is consequently contraindicated: serious hepatic impairment, hypotension (blood pressure < ninety/50 mmHg), current record of stroke or myocardial infarction and recognised hereditary degenerative retinal Conditions such as retinitis pigmentosa (

Prolonged erections and priapism are actually documented with sildenafil in write-up-internet marketing practical experience. In the function of the erection that persists for extended than 4 several hours, the affected person really should request fast health care aid.Nitric oxide then activates the enzyme guanylate cyclase, which ends up in enhan